The Washington Post and other news outlets failed their readers last week with a story promoting a grossly flawed phthalate study accompanied by a number of vague and unsupported editorial views of one of its authors – a long-standing phthalate opponent who has made a career of misleading the public regarding the safety of this thoroughly tested and widely used class of chemicals.
The media chose not to do any independent analysis of a key U.S. FDA finding, which the agency has reaffirmed on three separate occasions: no credible evidence connects phthalates in food packaging with any human health risk.
Reporters also ignored their responsibility to scrutinize the conclusions of the study at the center of the story, which falsely alleged that some 356,000 cardiovascular disease (CVD) deaths globally were attributed to exposure to the phthalate DEHP. Instead, they generally accepted the study’s findings at face value, and used statements from activists who’ve spent the majority of their careers opposing phthalates to corroborate the study’s claims.
News stories were replete with references from an anti-phthalate advocate, Dr. Leo Trasande, who used terms such as “may,” “could,” and “probably” in an attempt to form a causal leap between phthalates and potential human health risks. That simply isn’t good enough, and flies in the face of even the broadest definition of responsible journalism. And it falls far below even the lowest evidence standard that would otherwise warrant national media attention.
This study – like many we encounter regularly – has no scientific credibility and isn’t worth the digital ink it’s printed on. It was also partially funded by Beyond Petrochemicals, an activist group established by Michael Bloomberg to attack the chemical industry. Let’s consider a few critical details from the study the Post chose to withhold from its readers.
Questionable data
First, the study’s conclusion that DEHP exposure is linked to CVD mortality is based on very weak evidence. As the study itself notes:
“Certain regions, such as Africa, had fewer studies available on phthalates, which may result in higher error of estimated values.”
In Europe, the researchers only had access to data from certain countries, and those studies sometimes excluded adult age groups, “limiting the generalisability of their exposure measurements.”
For the United States, “estimates in this model are primarily based on findings from a single study…”
Put simply, the researchers can’t attribute elevated CVD deaths to DEHP exposure if they don’t know how much of the chemical these diverse populations are exposed to. This limitation led the study authors to concede that their results may prove unreliable:
“This burden model is the initial analysis of its kind as [sic] is subject to recalculation for reliability.”
In fact, there is so much uncertainty in the study’s model that it could have been used to argue that zero deaths are associated with DEHP exposure.
Confounding variables
Research that links chemical exposure with disease risk often runs into the reality that health conditions like CVD have multiple causes that can amplify each other. For instance, smoking and obesity are known causes of CVD that create a synergistic effect that increases risk beyond the sum of their individual impacts. This very well might explain the CVD risk this new study attributes to phthalate exposure, again as the authors themselves acknowledge:
“For example, an Italian study documented associations between PVC microplastics, which commonly contain phthalates, and adverse CV outcomes … However, this single country analysis was not confirmed in another industrialising country … which may have different dietary habits, cigarette smoke exposure, physical activity and other cardiovascular risks.”
It can be argued the link between CVD risk and DEHP exposure is entirely coincidental. People who smoke, eat unhealthy diets and limit their exercise – documented causes of CVD – are also exposed to phthalates. But it is entirely unproven that phthalate exposure on its own can cause CVD. This is a point McGill University chemist Dr. Joe Schwarz has stressed as well.
A related possibility, overlooked by the study authors, is that patients treated for CVD face higher DEHP exposure due to their treatment, rather than DEHP causing their cardiovascular disease. This phthalate is used in lifesaving medical equipment, including IV bags, tubing, catheters, and blood bags. It is reasonable to suggest that individuals with CVD have greater exposure to DEHP due to their reliance on these devices.
Conclusion
Bottom line: the press uncritically promoted a study funded and conducted by anti-chemical activists. These articles were each several hundred words, yet they gave an industry representative just two sentences to respond to all the claims made in the research. This wasn’t balanced, unbiased journalism: It was slanted advocacy designed to manipulate rather than inform. The public deserves better.